The slippery elm tree is native to North America, where it still primarily grows. The inner bark of the tree provides the greatest therapeutic benefit. In what conditions might slippery elm be supportive? common cold/sore throat cough Crohn’s disease gastritis Historical or traditional use: Native Americans found innumerable medicinal and other uses for this handy tree. Canoes, baskets, and other household goods were made from the tree and its bark. Slippery elm was also used internally for everything from sore throats to diarrhea.1 As a poultice, it was considered a remedy for almost any skin condition.